Tag: pharmacokinetics
Partial AUC in Bioequivalence: How Advanced Metrics Ensure Drug Safety and Efficacy
Partial AUC is a precise pharmacokinetic tool used to assess bioequivalence in complex drug formulations. Unlike total AUC, it focuses on specific time windows critical for drug effectiveness and safety-especially for extended-release and abuse-deterrent products. Regulators like the FDA now require it for over 127 drug products.
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Benzodiazepines pose serious risks for seniors-including falls, memory loss, and dementia. Learn why doctors now recommend avoiding them and what safer, proven alternatives exist for anxiety and insomnia.
Published ON: 15 JanLong-term steroid use suppresses natural cortisol production. ACTH stimulation testing is the only reliable way to safely determine when your adrenal glands have recovered enough to stop replacement therapy. This guide explains how the test works, when to do it, and why skipping it can be life-threatening.
Published ON: 17 JanPerformance-enhancing drugs give athletes quick results but come with severe, often permanent health risks. Learn how steroids, SARMs, and other substances affect the heart, hormones, and tendons-and what safer alternatives actually work.
Published ON: 3 JanStatins and certain antifungals can cause dangerous drug interactions that raise the risk of muscle damage. Learn which combinations are risky, safer alternatives, and what to do if you're taking both.
Published ON: 10 JanTurmeric and curcumin supplements can dangerously increase bleeding risk when taken with blood thinners like warfarin or aspirin. Real cases show INR levels spiking to life-threatening levels. Avoid combining them without medical supervision.
Published ON: 19 Jan