Fluorometholone: What It Is, How It Works, and What Alternatives Exist

When your eyes are red, itchy, or swollen, Fluorometholone, a low-potency corticosteroid eye drop used to treat inflammation caused by allergies, injuries, or eye conditions. Also known as FML, it’s one of the most commonly prescribed steroid eye treatments for mild to moderate eye inflammation. Unlike stronger steroids, Fluorometholone is designed to reduce the risk of side effects like increased eye pressure or cataracts — making it a go-to for short-term use under a doctor’s supervision.

It works by calming down the immune response in your eye tissue. When your body overreacts to pollen, dust, or an infection, it releases chemicals that cause swelling. Fluorometholone blocks those signals, bringing relief without shutting down your entire immune system. It’s not an antibiotic, so it won’t kill bacteria or viruses. But if your eye is inflamed because of an allergy, a scratch, or even after surgery, this drop can make a real difference. Many patients notice less redness and burning within a few days. Still, you shouldn’t use it longer than your doctor recommends — even if it feels better.

People often ask what else works like Fluorometholone. Prednisolone, a more potent steroid eye drop is sometimes used for serious inflammation, but carries higher risks. Loteprednol, another mild steroid is similar to Fluorometholone in safety and use, and sometimes preferred for long-term cases. Then there are non-steroid options like Antihistamine eye drops, used for allergic conjunctivitis — these help with itching but don’t reduce swelling as well. Your doctor picks based on your condition, how long you need treatment, and your eye health history.

Fluorometholone isn’t for everyone. If you have glaucoma, a fungal eye infection, or a corneal ulcer, it could make things worse. That’s why it’s always prescribed, never sold over the counter. Even if you’ve used it before, don’t reuse old bottles or share them. Contamination can lead to serious infections. And if your symptoms don’t improve in a week, or get worse, see your eye doctor right away — something else might be going on.

Below, you’ll find real comparisons and guides on how Fluorometholone stacks up against other eye treatments. Some posts dig into how it’s used after cataract surgery. Others compare it to non-steroid options for chronic allergies. You’ll also find advice on avoiding common mistakes — like using it too long or skipping follow-up visits. Whether you’re a patient trying to understand your prescription or a caregiver helping someone manage eye inflammation, these guides give you the facts without the fluff.